The first season of Coke Studio began on 7 June 2008 and ended on 4 August. The show was produced by The Coca-Cola Company and Rohail Hyatt. The production team included Rohail Hyatt as the executive producer along with Umber Hyatt being the producer of the show. Natasha De Souza, Nofil Naqvi and Naseer-ud-din Wasif served as production team members.

The second series of Coke Studio included notable differences from the first series, including the fact that the live audiences were excluded. The series also ran for longer, this time there were five episodes in total and in each episode there were five or more performances by the featuring artists. Rohail Hyatt returned as the executive producer along with Umber Hyatt as the producer of the show. This series also saw an increase in the number of musicians in the house band. The house band included, Asad Ahmed and Omran Shafique on guitars along with Kamran Zafar on bass guitars, two new members included Jaffar Zaidi on keyboards and Javed Iqbal on violin whereas Louis 'Gumby' Pinto returned on drums and on dholak was Sikander Inam. Other musicians included Natasha De Sousa and Saba Shabbir on backing vocals and on percussions were Babar Khanna, Waris 'Baloo' Ali and Zulfiq 'Shazee' Ahmed Khan.

Coke Studio returned for its third series on June 6, 2010. Rohail Hyatt continued as the executive producer along with Umber Hyatt as the producer of the show. The production team included Naseer-ud-din Wasif as the technical manager, Zeeshan Parwez assisted by Adnan Malik on video production, Danial Hyatt on visual and animations and Selina Rashid with her firm Lotus as public relations.

Rohail Hyatt and his wife Umber Hyatt remained as the producers of the show. The houseband recruited drummer Raheel Manzar Paul and vocalist Rachel Viccaji. The houseband saw Sanam Saeed and Saba Shabbir leaving the band and the rest of the house band remained unchanged.

Coke Studio returned for its fifth series on 13 May 2012. Rohail Hyatt and Umber Hyatt continued as producers of the show. Among the houseband, Louis 'Gumby' Pinto left the show due to his being the executive producer of the show Uth Records by Ufone. Jaffer Ali Zaidi also left the show and was replaced by Mubashir Admani. Raheel Manzar Paul and Zulfiq 'Shazee' Ahmed Khan also left the show. Farhad Humuyun was recruited as the new drummer for the fifth series.